| 効果 | なし |
| 試験方法 | コホート法 |
| 試験期間 | 不明 |
| 被験者数 | 61 |
| 性別 | 不明 |
この研究の注釈：
When CLA (80% c9t11, 20% t10,c12) comprised 7% of their 2600kcal (average, but individualized) diet (using oleic acid as control, 20g CLA daily) for 21 days in a cross-over design found no differences in measured inflammatory parameters compared to oleic acid (TNF-RI, TNF-RII, MCP-1, IL-6, CRP) but found a significant (170%) increase in urinary 8-iso-PGF2α, a prostaglandin.
When CLA (80% c9t11, 20% t10,c12) comprised 7% of their 2600kcal (average, but individualized) diet (using oleic acid as control, 20g CLA daily) for 21 days in a cross-over design found no differences in measured inflammatory parameters compared to oleic acid (TNF-RI, TNF-RII, MCP-1, IL-6, CRP) but found a significant (170%) increase in urinary 8-iso-PGF2α, a prostaglandin.
Weight was not measured.
Effects Of Dairy Products Naturally Enriched With Cis-9,trans-11 Conjugated Linoleic Acid On The Blood Lipid Profile In Healthy Middle-aged Men
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 不明 |
| 被験者数 | 32 |
| 性別 | 不明 |
この研究の注釈：
6 weeks of consumption of dairy products containing 1.421g CLA daily do not influence any of the above parameters such as weight or blood lipids.
Conjugated Linoleic Acid Supplementation, Insulin Sensitivity, And Lipoprotein Metabolism In Patients With Type 2 Diabetes Mellitus
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 32 |
| 性別 | 男女 |
| 年齢 | 45-64 |
| 体型 | 肥満 |
この研究の注釈：
Glucose was significantly increased by 6.3% and insulin sensitivity (assessed by HOMA) decreased after type II diabetic patients consumed 3g CLA daily for 8 weeks. No effects on CRP or IL-6, and HDL-C increased by 8%.
Conjugated Linoleic Acid Supplementation For 8 Weeks Does Not Affect Body Composition, Lipid Profile, Or Safety Biomarkers In Overweight, Hyperlipidemic Men
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 27 |
| 性別 | 男性 |
| 年齢 | 30-44, 45-64 |
| 体型 | 肥満 |
この研究の注釈：
Relative to safflower oil as a control at 3.5g daily, two experimental groups were used. 3.5g of oil comprising 2.7g of 50/50 CLA isomers, and 3.5g oil comprising 2.7g of jsut the c9t11 isomer. Population was overweight and hyperlipidemic men, and no dietary controls were in place (free-living conditions) over 56 days.
Relative to safflower oil as a control at 3.5g daily, two experimental groups were used. 3.5g of oil comprising 2.7g of 50/50 CLA isomers, and 3.5g oil comprising 2.7g of jsut the c9t11 isomer. Population was overweight and hyperlipidemic men, and no dietary controls were in place (free-living conditions) over 56 days.
No differences existed in lean mass, fat mass, or weight; nor were any trends noted. A decrease in circulating TNF-a was noted with both CLA treatments, and all other parameters came back statistically insignificant.