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dehydroepiandrosterone-insulin-sensitivity

Lack Of Dehydroepiandrosterone Effect On A Combined Endurance And Resistance Exercise Program In Postmenopausal Women

効果 なし
試験方法 二重盲検法
試験期間 1-6 ヶ月
被験者数 31
性別 女性
年齢 45-64, 65+
体型 トレーニングしてない, 肥満
この研究の注釈:

50mg of DHEA over 12 weeks in healthy postmenopausal women with an average age of 64.6yrs and who were sedentary at the start of the study.

With the introduction of exercise, beneficial changes in body composition were due to exercise and there was no difference in the DHEA group relative to placebo.

A reduction in small dense LDL particles (oxidized LDL usually) was noted.

研究の資金源に関する問題点:

NIH grant, likely a nonissue


Dehydroepiandrosterone Replacement In Healthy Men With Age-related Decline Of DHEA-S: Effects On Fat Distribution, Insulin Sensitivity And Lipid Metabolism
効果 なし
試験方法 二重盲検法
試験期間 1-6 ヶ月
被験者数 12
性別 男性
年齢 45-64
体型 肥満
この研究の注釈:

50mg of DHEA given for 3 months in a double blind manner to aged men with low circulating DHEA levels but otherwise healthy status was unable to significantly influence any study parameter despite increasing circulating DHEA levels. The only effect that was notable was an increasing trend to increase LDL and Triglycerides, which did not reach statistical significance.


Effects Of Dehydroepiandrosterone (DHEA) Supplementation On Hormonal, Metabolic And Behavioral Status In Patients With Hypoadrenalism
効果 なし
試験方法 コホート法
試験期間 1-6 ヶ月
被験者数 20
性別 男女
年齢 30-44, 45-64
体型 肥満
この研究の注釈:

DHEA at 50mg for 4 months was unable to influence serum testosterone levels in men, while it increased testosterone levels only in women with low circulating androgens. SHBG dropped in men and women, and DHEA-S in serum increased in both groups.

No effects on carbohydate metabolism or insulin sensitivity were seen. Fat mass decreased, no effects on well being and quality of life were seen.

Patients were hypoadrenics.


管理人 :慶應義塾大学の理工学部卒業後、国内外でコンサルティング業務やスタートアップの立ち上げを経験した後、日本に帰国してから健康・医療の情報を収集して発信しています。 趣味:ネットサーフィン、読書(最近かなり減ってますが)、アウトドア(家族と) 毎日メディテーションとジョギング、筋トレ・ストレッチしています。既婚で子供4人(男女女男)です。