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trimethylglycine-salivation

Evaluation Of The Clinical Efficacy Of A Betaine-containing Mouthwash And An Intraoral Device For The Treatment Of Dry Mouth

効果 増加
試験方法 コホート法
試験期間 2-4 週間
被験者数 90
性別 男女
年齢 65+
この研究の注釈:

In an unblinded study, the efficacy of a 1.33% betaine mouthwash was tested and found to improve symptoms of dry mouth induced by pharmaceuticals over the course of four weeks; the benefits were not additive with an intraoral device (mouthguard) despite the two being comparable in efficacy.

No placebo control, symptoms relative to baseline and 63% of persons reported benefit from treatment (7 ratings of beneficial, 12 of minor benefit, none of major benefit, 10 reporting no change, 1 worsening).


Safety And Effectiveness Of Topical Dry Mouth Products Containing Olive Oil, Betaine, And Xylitol In Reducing Xerostomia For Polypharmacy-induced Dry Mouth
効果 増加
試験方法 コホート法
試験期間 1-7 Days
被験者数 40
性別 男女
年齢 65+
この研究の注釈:

A pilot study tested a 1.33% betaine solution (albeit with olive oil and xylitol possibly also being bioactive) has noted benefits to dry mouth symptoms relative to unblinded control.


Betaine-containing Toothpaste Relieves Subjective Symptoms Of Dry Mouth
効果 増加
試験方法 コホート法
試験期間 1-2 週間
被験者数 13
性別 女性
年齢 65+
この研究の注釈:

Twice daily brushing of a toothpaste containing 4% betaine by weight in persons with dry mouth symptoms appears to be able to reduce said symptoms as assessed by self-reported, with no apparent changes in the visual appearance of the mucosa or bacterial colonies. Efficacy was greater in those with worse symptoms and lower baseline salivation rates.


管理人 :慶應義塾大学の理工学部卒業後、国内外でコンサルティング業務やスタートアップの立ち上げを経験した後、日本に帰国してから健康・医療の情報を収集して発信しています。 趣味:ネットサーフィン、読書(最近かなり減ってますが)、アウトドア(家族と) 毎日メディテーションとジョギング、筋トレ・ストレッチしています。既婚で子供4人(男女女男)です。