A standardized Withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study

効果 減少
試験方法 二重盲検法
試験期間 1-6 ヶ月
被験者数 98
性別 男女
年齢 18-29, 30-44, 45-64
この研究の注釈：

Chronically stressed people taking an ashwagandha extract for 60 days saw improvements with regard to anxiety, well-being, and serum health parameters. Cortisol decreased (by 14.5% for 125 mg/day, 24.2% for 250 mg/day, and 30.5% for 500 mg/day), as did LDL-C (by 17.4% for 500 mg/day) and VLDL-C (by 23.9% for 500 mg/day), while HDL-C increased (by 17.3% for 500 mg/day).

研究の資金源に関する問題点：

Authors are involved with companies that produce ashwagandha supplements, Nutragenesis and Natreon

Hypoglycemic, Diuretic And Hypocholesterolemic Effect Of Winter Cherry (Withania Somnifera, Dunal) Root

効果 減少
試験方法 コホート法
試験期間 1-6 ヶ月
被験者数 12
性別 男女
体型 肥満, 平均
この研究の注釈：

6 persons with Type II diabetes and 6 persons with high cholesterol demonstrated lipid lowering effects, anti-glycemic effects, and a diuretic effect.

Exploratory Study To Evaluate Tolerability, Safety, And Activity Of Ashwagandha (Withania Somnifera) In Healthy Volunteers

効果 減少
試験方法 コホート法
試験期間 1-6 ヶ月
被験者数 17
性別 男女
年齢 18-29
体型 平均
この研究の注釈：

In an exploratory toxicological study in otherwise healthy persons, supplementation of a water extract at 750 mg for 10 days followed by 1,000 mg and 1,250 mg for 10 days each (equivalent to 6 g, 8g , and 10 g of the dry root) noted a 9.3% reduction in total cholesterol which was thought to be due to LDL cholesterol (trending to decrease) and a significant increase in strength in the quadricep and back extensor muscles (but not grip) was noted after 30 days despite no exercise.