creatine-heart-rate

5 g taken four times a day (20 g/day) for 6 days was able to improve intermittent sprint performance (a 50-m sprint conducted six times with a 2-minute break in between). The decrease in speed on the third sprint was reduced from 5% to 2%, but was nonsignifiant after the sixth sprint. Biochemical parameters (heart rate, lactate, creatinine) were unaltered.

300 mg/kg/day for 7 days increased body mass (0.75 kg) and power output during sprints in the heat, but did not appear to influence heat tolerance or any parameter of cardiovascular health. A greater (relative to placebo) exercise-induced increase in aldosterone was also noted.

20 g/day for 5 days followed by 2 g/day for 37 days in healthy sedentary omnivorous males increased muscle creatine but failed to improve VO~2~ max. Performance on intermittent sprints increased after the 5 days of loading (7.03±1.0% in the creatine group versus 3.06±1.4% in the placebo group), but the improvement after the 37 days of maintenance was not statistically significant.