Long-term Low-dose Dehydroepiandrosterone Oral Supplementation In Early And Late Postmenopausal Women Modulates Endocrine Parameters And Synthesis Of Neuroactive Steroids

この研究の注釈:

25mg of DHEA over 12 months was able to increase all steroid hormones in the serum, including the neurosteroids allopregnanolone and beta-endorphin. SHBG also decreased alongside cortisol, and overall menopausal symptoms in these women was decreased.


Six-month Oral Dehydroepiandrosterone Supplementation In Early And Late Postmenopause

この研究の注釈:

50mg of DHEA over 6 months in menopausal women showed that testosterone and estrogen increased, while SHBG decreased only in overweight women significantly. Plasma levels of neurosteroids (beta-endorphin and allopregnanolone) increased while cortisol and gonadotropins decreased.

SHBG decreased only in the subset of postmenopausal women who were older and overweight.