| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 6+ ヶ月 |
| 被験者数 | 85 |
| 性別 | 女性 |
| 年齢 | 45-64 |
| 体型 | 平均 |
この研究の注釈：
60mg Icariin (with 15mg [Daidzein] and 3mg [Genistein]) paired with 300mg elemental calcium daily over the course of 2 years in post-menopausal women was able to attenuate decreases in bone mineral density over the trial period.
60mg Icariin (with 15mg [Daidzein] and 3mg [Genistein]) paired with 300mg elemental calcium daily over the course of 2 years in post-menopausal women was able to attenuate decreases in bone mineral density over the trial period.
No adverse changes in estrogen were seen despite co-consumption of phytoestrogens.
Bioassays For Estrogenic Activity: Development And Validation Of Estrogen Receptor (ERalpha/ERbeta) And Breast Cancer Proliferation Bioassays To Measure Serum Estrogenic Activity In Clinical Studies
| 効果 | なし |
| 試験方法 | コホート法 |
| 試験期間 | 不明 |
| 被験者数 | 8 |
| 性別 | 不明 |
この研究の注釈：
8 subjects between the age of 21 and 65 of non-obese status and otherwise healthy men were given Epimedium extract and tested for estrogenicity.
8 subjects between the age of 21 and 65 of non-obese status and otherwise healthy men were given Epimedium extract and tested for estrogenicity.
A 6% increase in effects on ERa (one of two estrogen receptors) was seen after supplementation, but effects on ERb and overall estrogen/17b-estradiol levels were unaffected; if anything there was a non-significant decline.
Oral dose was 50g of a hot water extract of Epimedium Pubescens.
