Characterization Of The Metabolic And Physiologic Response To Chromium Supplementation In Subjects With Type 2 Diabetes Mellitus

この研究の注釈:

Supplementation of 1mg chromium (in the form of chromium picolinate) in two divided doses daily for 24 weeks in type II diabetics noted that while there was a trend to increase insulin sensitivity, this was not statistically significant and only 46% of persons were considered responders.

No other changes were noted in diet, glucose metabolism, and the response to chromium was more associated with baseline insulin resistance rather than the kinetics of chromium after ingestion.


Antioxidant Effects And Insulin Resistance Improvement Of Chromium Combined With Vitamin C And E Supplementation For Type 2 Diabetes Mellitus

この研究の注釈:

In type II diabetics with an HbA1c over 8.5% given 1mg of chromium via yeast, supplementation was associated with a reduction in blood glucose (11%) and HbA1c (0.7%, from 10.2% to 9.5%) alongside an increase in insulin sensitivity.

Lipid peroxidation, as assessed by TBARS, was also reduced with chromium by 18.7%. An increase in glutathoine peroxidase was noted, but catalase and SOD were unaffected.


Effects Of Chromium Picolinate On Food Intake And Satiety

この研究の注釈:

In overweight women reporting intense carbohydrate cravings at least twice a week, supplementation of 1,000mcg chromium appeared to reduce hunger and cravings over the course of weight weeks which resulted in a greater reduction in overall food intake (25%) than did placebo (8%). This reduction in food intake led to weight loss, but was independent of any changes in glucose metabolism.


Chromium Picolinate Does Not Improve Key Features Of Metabolic Syndrome In Obese Nondiabetic Adults

この研究の注釈:

Chromium supplementation at 1,000mcg daily (as picolinate) increased the acute insulin response to glucose but failed to influence any other measured parameter of metabolic syndrome after 16 weeks supplementation in adults with signs of metabolic syndrome yet no diagnosed diabetes.